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  • 1 -4 (28/1) 2019 — Agzamkhodjaev T. S., Nurmukhamedov Kh. K., — CHANGES IN EEG AND BISPECTRAL INDEX IN CHILDREN DURING INHALATION ANESTESIA OF CARDIOCURGERU OPERATION

1 -4 (28/1) 2019 — Agzamkhodjaev T. S., Nurmukhamedov Kh. K., — CHANGES IN EEG AND BISPECTRAL INDEX IN CHILDREN DURING INHALATION ANESTESIA OF CARDIOCURGERU OPERATION

CHANGES IN EEG AND BISPECTRAL INDEX IN CHILDRENDURING INHALATION ANESTESIA OF CARDIOCURGERU OPERATION

Agzamkhodjaev T. S., Tashkent Pediatric Medical Institut

Nurmukhamedov Kh. K., Tashkent Pediatric Medical Institut

Tohirov Sh. M., Tashkent Pediatric Medical Institut

Solihodjaev Sh. I., Tashkent Pediatric Medical Institut

Mamatkulov I. B., Tashkent Pediatric Medical Institut

Ismayeova M. U. Tashkent Pediatric Medical Institut

Resume

Objective: to estimate bispectral (BIS) index and electroencephalographic (EEG) changes during anesthesia with izoflurane, sevoflurane, and a successive combination of sevoflurane and izoflurane, by taking into account age.

Subjects and methods. Sixty children aged 3 to 17 years, who had undergone cardiosurgery operation, were randomized to 3 groups of 20 children each: 1) izoflurane anesthesia; 2) sevoflurane anesthesia; and 3) a successive combination of sevoflurane and izoflurane. A 1:1 oxygen-nitrous oxide mixture was used for anesthesia in all the groups. EEG (using a 6-channel computer-assisted encephalograph) and bispectral index (XP version) was continuously recorded throughout the anesthesia, except the transition to izoflurane in Group 3.

Results. In the izoflurane group, EEG displayed a gradual reduction in basic rhythm, an increase in slow activity with the rhythm being recovered on emergence. The BIS index changed from 96-99 to 19-36 with a spike of up to 80­87 on emergence. In Groups 2 and 3 where the induction of anesthesia used sevoflurane, EEG recorded a pointed aa– rhythm, increased amplitude, and rhythm synchronization. The BIS value changed from 96-99 to 19-37. In Group 2, it was 30 to 40 on anesthesia maintenance and up to 82-87 on emergence. In Group 3, the izoflurane anesthesia stage changed EEC patterns towards rhythm synchronization and gave rise to slow fluctuations in all leads. The BIS index was 30-39 on anesthesia maintenance and 80-86 on emergence.

Conclusion. EEC and BIS index monitoring values corresponded to the clinical course and depth of anesthesia. The comparison of the clinical data of the course of anesthesia and the values of EEG and BIS monitoring could lead to the conclusion that BIS technology might be of informative value in children.

Key words: inhalation anesthesia, electroencephalography, BIS monitoring, sevoflurane, isoflurane

First page

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Last page

14

For citation: Агзамходжаев Т.С., Нурмухамедов Х.К., Тохиров Ш.М., Солиходжаев Ш.И., Маматкулов И.Б., Исмаиёова М.У. Changes in eeg and bispectral index in children during inhalation anestesia of cardiocurgeru operation//New Day in Medicine 4(28)2019 8-14 https://cutt.ly/7byjM2I

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