72 -1 (29/2) 2020 — Matrizayeva G.D., Ikramova Kh.S — CURRENT METHODS OF TREATMENT OF INFERTILITY ASSOCIATED WITH POLYCYSTIC OVARIAN SYNDROME
CURRENT METHODS OF TREATMENT OF INFERTILITY ASSOCIATED WITH POLYCYSTIC OVARIAN SYNDROME
Matrizayeva G.D., Urgency branch of Tashkent Medical Academy.
Ikramova Kh.S, Urgency branch of Tashkent Medical Academy.
Rajabova G.O., Urgency branch of Tashkent Medical Academy.
Resume,
The aim of this work was to estimate the cumulative effectiveness of stimulation of ovulation in women with polycystic ovarian syndrome (PCOS) of different age groups. The design methods: Investigation included 79 women aged 21 to 40 years old with PCOS associated infertility. Ovarian stimulation with the use of antiestrogens (clomiphene citrate) and aromatase inhibitor letrozole. The final points were: the level of Human Chorionic Gonadotropin was more than 100 international units on the day 14 after ovulation and visualization of the ovum by ultrasound investigation on the day 21 after ovulation. Conclusions: Ovarian stimulation was the most effective in women with PCOS younger than 30 years old. Among the patients older than 35 years, old ovarian stimulation only was not effective.
Key words: polycystic ovarian syndrome, stimulation of ovulation, age.
First page
265
Last page
267
For citation: Matrizayeva G.D., Ikramova Kh.S., Rajabova G.O., Current methods of treatment of infertility associated with polycystic ovarian syndrome//New Day in Medicine 1(29)2020 265-267 https://cutt.ly/IvNWjJT
List of References
- Ихтиярова Г.А., Рахматуллаева М.М., Гинекологияда гормонал терапия. Бухоро, /Ўкув қўлланма 2019 й. № 354-412
- Кирющенков А.П., Совчи М. Г. Поликистозные яичники. Акушерство и гинекология. 1994; 1: 11-14.
- Козуб Н.И. Поликистоз яичников. // Международный медитцинский журнал. 1998; 4: 67-70
- Gasparov A.S. The clinic, diagnosis and long-term results of treatment of infertility in patients with polycystic ovary syndrome: Abstract diss. Moscow; 1996: 274 p.
- Nazarenko T.A. Polycystic ovary syndrome: a modern approach to the diagnosis and treatment of infertility. 2nd ed. Moscow: MEDpress-info; 2008: 21-51. (in Russian)
- Sheehan M.T. Polycystic ovarian syndrome: diagnosis and management. Clin. Med. Res. 2004; 2 (1): 13-27.
- Shargorodskaya A.V., Pishchulin A.A., Melnichenko G.A. Polycystic ovary syndrome in age aspect (review). Problemy reproduktsii. 2003; 9 (11): 28-32. (In Russian)
- Antsiferov M.B., Grigoryan Shch.R., Chernova T.O. Features of the drug Siofor (metformin hydrochloride) in women with polycystic ovary syndrome and overweight. Problemy reproduktsii. 2001; 2: 49-55. (in Russian)
- Nazarenko T.A., Gasparov A.S., Kuz’michev L.N., Kalinina E.A. Features of infertility treatment in patients with polycystic ovary syndrome, including IVF. In: In vitro fertilization and new directions in the treatment of male and female infertility. Moscow, 2004; 470-96. (in Russian)
- Mitwally M. F. M., Casper R. F. Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate // Fertil. Steril. – 2001; – Vol. 75.305-309.
- Pritts E. A. Letrozole for ovulation induction and controlled ovarian hyperstimulation // Current Opinion Obstet.