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  • 136 -1 (29/3) 2020 — Rahmanov R.R., — HISTOPHYSIOLOGY OF THE SUPERFICIAL JUXTAMEDULLARY VASCULAR RENAL GLOMERULI AFTER ACUTE MASSIVE BLOOD LOSS

136 -1 (29/3) 2020 — Rahmanov R.R., — HISTOPHYSIOLOGY OF THE SUPERFICIAL JUXTAMEDULLARY VASCULAR RENAL GLOMERULI AFTER ACUTE MASSIVE BLOOD LOSS

HISTOPHYSIOLOGY OF THE SUPERFICIAL JUXTAMEDULLARY VASCULAR RENAL GLOMERULI AFTER ACUTE MASSIVE BLOOD LOSS

Rahmanov R.R., Andijan State Medical Institute.

Resume,

The aim of the investigation was to study the state of juxtaglomerular apparatus (JGA) and capillaries of the superficial and juxtamedullary vascular renal glomeruli after acute massive blood loss.

Material and methods: the degree of opening the capillaries (DOCC) of the superficial and juxtamedullary vascular glomeruli, the ultrastructure of JGA were studying morphologically in experiments in 60 outbred white male rats with body mass 120-140g before and after acute massive blood-letting (on average 3.0 cm3 or 2.5% of the body mass) in 1, 2 and 24 hours.

Results: Within 1-2 hours after blood loss the lessening of the circulating blood volume causes a spasm of the afferent and dilatation of the efferent arterioles, the capillaries of the superficial and juxtamedullary vascular glomeruli have mainly I and II DOCC (up to 20%); the average value of DOCC in both cortex zones smooth down. JGA is in the state of functional stress. Within 24 hours after blood loss DOCC and JGA structure become almost normal.

Conclusion: the data obtained suggest that activity of the superficial and juxtamedullary vascular glomeruli under physiological conditions and after acute massive blood-letting is regulated by activity of JGA.

Key words: kidneys, cortex, glomerular capillaries, blood loss, JGA, blood flow.

First page

501

Last page

504

For citation: Rahmanov R.R., Histophysiology of the superficial juxtamedullary vascular renal glomeruli after acute massive blood loss//New Day in Medicine 1(29)2020 501-504 https://cutt.ly/1bqxUEv

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