109 -2 (30/3) 2020 — Kurbanov B.B., ‘Kurbanov D.D., — FEATURES OF PATHOLOGIC CHANGES IN THE PLACENTA IN PREGNANT WOMEN WITH HYPERTENSION

FEATURES OF PATHOLOGIC CHANGES IN THE PLACENTA IN PREGNANT WOMEN WITH HYPERTENSION

Kurbanov B.B., –Tashkent Pediatric Medical Institute. 223, Bagishamal Street, Tashkent, 100140. Uzbekistan. Website: http://tashpmi.uz

Kurbanov D.D., –Tashkent Pediatric Medical Institute. 223, Bagishamal Street, Tashkent, 100140. Uzbekistan. Website: http://tashpmi.uz

Jalolov R.K., –Tashkent Pediatric Medical Institute. 223, Bagishamal Street, Tashkent, 100140. Uzbekistan. Website: http://tashpmi.uz

Kurbanova M. T., –Tashkent Pediatric Medical Institute. 223, Bagishamal Street, Tashkent, 100140. Uzbekistan. Website: http://tashpmi.uz

Magrupov B.A., -Tashkent Institute of Postgraduate Medical Education, 100007 Uzbekistan Tashkent,
Parkent 51 https://t.me/tashiuv.

Resume,

Despite of numerous studies in obstetrics on the problem of hypertensive conditions, many issues of etiology and pathogenesis remain controversial. The development is based on a pathological change in the processes of implantation and placentation, the first manifestation of which is a violation of the migration of cytotrophoblast cells. This article provides current data on changes in the placenta in pregnant women with various degrees of hypertensive conditions.

Key words: Preeclampsia, placenta, trophoblast.

First page

416

Last page

420

For citation: Kurbanov B.B., Kurbanov D.D., Jalolov R.K., Kurbanova M. T., Magrupov B.A., Features of pathologic changes in the placenta in pregnant women with hypertension//New Day in Medicine 2(30)2020 416-420 https://cutt.ly/dvIUb0r

List of References

  1. Ahmedov F.K. et al. Cardiac and renal hemodynamics in pregnant women with pre-eclampsia against the background of obesity (in Russian) // International Journal of Applied and Basic Research. – 2013. – №. 11-2. – pp. 18-20.
  2. Ikhtiyarova G.A., Negmatullaeva M.N., Tuksanova D.I. Modern aspects of correction of hemodynamic disorders in pregnant women with mild pre-eclampsia // Pediatrics (Uzbek). -2003. -Special issue. -pp. 97-99.
  3. Macatzaria A.D., Bitsadze V.O. Thrombophilic conditions in obstetric practice. -Moscow, 2001. -p.543.
  4. Makarov O.V., Volkova E.V., Dzhokhadze L.S. Prospects of Diagnostics and Forecasting of Preeclampsia. Rosvestnik obstetrician gynecological 2012;1: pp.35-42.
  5. OsipovaN.A. Makarov O.V., Poletaev A.B., BogatyrevYu.A. Clinical significance of autoantibodies in the pathogenesis of pre­eclampsia // Proceedings of the XII All-Russian Scientific Forum Mother and Child. Moscow 2011. – pp. 121-122.
  6. Shifman E.M. Preeclampsia, eclampsia, HELLP-syndrome. – Petrozvodsk, 2003. -p.56.
  7. Biasiutti F., Strebel J. Anticoagulation and antiaggregation during pregnancy //TherUmsch. -2003. -Vol.60, No. 1. -pp. 54-58.
  8. Fallahian M., Nabaie F. Subclinical thovbocytopenia and pre- eclampsia//Int J Gynec Obstet. -2005. -Vol. 89< №1. -pp. 47-48.
  9. Maynard S., Epstein F.H., Karumanchi S.A. Preeclampsia and angiogenic imbalance. Annu Rev Med 2008; 59: pp. 61-78.
  10. Tanjung M., Siddik H., Hariman H. Coagulation and fibrinolysis in pre-eclampsia and neonates //ClinApplThrombHemost. – – 2006. – Vol. 11, №4. -pp. 467-473.
  11. Kurbanov B. 138 The role of vascular endothelial growth factor as markers of hypertension induced pregnancy: Angiogenic // Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health. – 2016. – Т. 6. – №. 3. – p. 248.
  12. Kurbanov B. 77. The role of VEGF as prognostic marker of preeclampsia//Pregnancy Hypertension. – 2018. – T. 13. – P. S68.
  13. Kurbanov B. – p. s68. 13. The effectiveness of sflt1 protein for the diagnosis and prediction of hypertensive states in pregnant women/ Journal of Hypertension: July 2019 – Volume 37 – Issue – p e241. doi: 10.1097/01.hjh.0000573088.13152.fc
  14. Uzan J., Carbonnel M., Piconne O., Asmar R., Ayoubi J.-M. Pre-eclampsia: pathophysiology, diagnosis and management. Vascular health and risk management 2011; 7: pp.467-474.
  15. Myers J.E., Kenny L.C., McCowan L.M., Chan E.H., Dekker G.A., Poston L., Simpson N.A., North R.A. SCOPE consortium. Angiogenic combined with clinical risk to predict preterm pre­eclampsiain nulliparous women: apredictive test accuracy study. BJOG 2013; 120: 10: pp.1215-1223.
  16. H. K. Riise, G. Sulo, G.S. Tell [et al.] // Incident Coronary Heart Disease After Preeclampsia: Role of Reduced Fetal Growth, Preterm Delivery and Parity /// J. Am. Heart Assoc. 2017;6 (2)
  17. Hagmann H, Thadhani R, et al. The promise of angiogenic markers for the early diagnosis and prediction of pre-eclampsia. ClinChem 2012; 58 (5): pp.837-845.
  18. Cerdeira A.S., Karumanchi S.A. Angiogenic proteins as aid in the diagnosis of pre-eclampsia. Scandinavian Journal of Clinical and Laboratory Investigation 2010; 70 (Suppl 242): pp.73-78.

file

download