95 -3 (31/3) 2020 — Nasirova G.R., Turdieva Sh.T. — BACTERIOPHAGE THERAPY OF CHILDREN WITH ACUTE TONZILLITIS

BACTERIOPHAGE THERAPY OF CHILDREN WITH ACUTE TONZILLITIS

Nasirova G.R. -Tashkent Pediatric Medical Institute, Uzbekistan.

Turdieva Sh.T. -Tashkent Pediatric Medical Institute, Uzbekistan.

Resume

Aim. The study of the feasibility of conducting bacteriophage therapy on an outpatient basis in acute tonsillitis in children and adolescents.

Materials and methods. Examined 128 children from 3 to 14 years old with acute tonsillitis. Conducted general clinical research, pharyngoscopy, bacteriological examination of a smear of tonsils. Bacteriophage therapy carried out using a liquid complex pyobacteriophage (Pyobacteriophage complex liquid – PCL).

Results. It revealed that the main pathogens of acute tonsillitis in children were bacteria Staphylococcus aureus and Streptococcus pyogenes (from 24.2% to 42.2%). Conducting bacteriophage therapy led to a decrease in swelling in the tonsils and general intoxication signs by 2-3 days of treatment. In the blood, the level of leukocytes in 85.07% of patients returned to normal on the 4th day of the disease.

Conclusion. The main predictor of the development of acute tonsillitis in children is a viral infection (75.8%), which contributed to increased colonization of the tonsils by the pathogenic bacterial flora, mainly Staphylococcus aureu and Streptococcus pyogenes. The use of bacteriophage therapy in the conservative treatment of acute tonsillitis in children contributes 1.4 times to the most rapid relief of the acute period of the disease.

Key words: acute tonsillitis; children; the tonsils; bacterium; bacteriophage.

First page

400

Last page

403

For citation: Nasirova G.R., Turdieva Sh.T., Bacteriophage therapy of children with acute tonzillitis//New Day in Medicine 3(31)2020 400-403 https://cutt.ly/axD8XMX

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