131 -3 (31/3) 2020 — Ergashev F.Kh., Ruzikulov N.Ye., — FEATURES OF LIPID METABOLISM IN FAMILIES OF CHILDREN WITH ACUTE NON-RHEUMATIC CARDITA

FEATURES OF LIPID METABOLISM IN FAMILIES OF CHILDREN WITH ACUTE NON-RHEUMATIC CARDITA

Ergashev F.Kh. -Samarkand State Medical Institute.

Ruzikulov N.Ye. -Samarkand State Medical Institute.

Abdurasulov F.P. -Samarkand State Medical Institute.

Resume

Background. Myocardial lesions are a widespread form of cardiac pathology (CP) in children and are attracting increasing attention of pediatricians. Children from families with a family history of cardiac pathology show significant changes in lipid metabolism. These changes can be significantly exacerbated by inflammatory changes in the myocardium and deserve special study.

Purpose of the research. Coverage of the features of lipid metabolism in young children with acute non-rheumatic carditis, from families with a burdened cardiopathological family history.

Materials and methods. Observation were 84 children with acute non-rheumatic carditis at the age of 3 months. up to 3 years. In parallel with this group of patients, 38 sick children without burden of a family history of CP were examined. A general clinical examination and special biochemical research methods were performed for all sick children, as well as groups of relatives.

Results. Our data on the unidirectional changes in lipid fractions in parents and children do not contradict the existing literature data and indicate the undoubted role of heredity in these changes.Conclusion. The unidirectionality of lipid metabolism disorders in probands and in immediate relatives allows us to conclude that there is a risk of developing such disorders in practically healthy family members under the influence of adverse factors, which must be taken into account during family medical examination.

Keywords: non-rheumatic carditis, lipid metabolism, phospholipid.

First page

544

Last page

547

For citation: Ergashev F.Kh., Ruzikulov N.Ye., Abdurasulov F.P., Features of lipid metabolism in families of children with acute non-rheumatic cardita//New Day in Medicine 3(31)2020 544-547 https://cutt.ly/kxGt2ib

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