33 -4 (32/1) 2020 — Atakhodjaeva G.A., Mal G.S. — FUNCTIONAL CONDITION OF KIDNEYS IN PATIENTS WITH HEART FAILURE WITH LOW EJECTION FRACTION AND METABOLIC SYNDROME
FUNCTIONAL CONDITION OF KIDNEYS IN PATIENTS WITH HEART FAILURE WITH LOW EJECTION FRACTION AND METABOLIC SYNDROME
Atakhodjaeva G.A. -Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan,Kursk state medical university, Russian Federation.
Mal G.S., -Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan,Kursk state medical university, Russian Federation.
Bektimirova A.A. -Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan,Kursk state medical university, Russian Federation.
Resume
Objective: The aim of investigation was to study renal function in patients with heart failure with low ejection fraction and metabolic syndrome. A total of 88 male patients with chronic heart failure with a low ejection fraction of HFmrEF (EF> 40%) aged 40-60 were examined. 3 groups of patients were distinguished depending on the presence of MS components: Group I (n = 28), patients without MS; Group II (n = 28) patients with a different combination of DLP, AO and HTG, Group III (n = 32) patients with MS and diabetes. MS in patients with CHF aggravates impaired kidney function, which has developed as one of the main pathogenetic links CHF. It has been established that as MS progresses (joining of T2D to other components of MS), the phenomena of functional renal insufficiency increase.
Key words: chronic heart failure, ejection fraction, kidney function.
First page
146
Last page
150
For citation: Atakhodjaeva G.A., Mal G.S., Bektimirova A.A., functional condition of kidneys in patients with heart failure with low ejection fraction and metabolic syndrome//New Day in Medicine 4(32)2020 146-150 https://cutt.ly/3l4euIY
List of References
- Аляви Б.А. Метаболический сивдром // Учебно-методическое пособие. – Ташкент. – 2016г. – С. 15-33. Alyavi B.A.. Metabolic syndrome// Teaching aid. – Tashkent. – 2016. P15-33.
- Атаходжаева Г.А. Качество жизни и функциональное состояние почек у больных с хронической сердечной недостаточностью и метаболическим сивдромом // Журнал “Терапевтический вестник Узбекистана”, Ташкент, 2015 й, №2, 202207 стр. Atakhodjaeva G.A. Quality of life and functional state of kidneys in patients with chronic heart failure and metabolic syndrome // Therapeutic Journal of Uzbekistan, Tashkent, 2015, №2, p. 202207
- Атаходжаева Г.А., Рахимов 0.М. Роль метаболических факторов в развитии эндотелиалыний дисфункции у больных с хронической сердечной недостаточностью// Журнал “Кардиология Узбекистана” 2015 г., №1 (35), стр 42-46 Atakhodjaeva G.A., Rakhimov Sh. M. The role of metabolic factors in the development of endothelial dysfunction in patients with chronic heart failure// Jourmal of Cardiology of Uzbekistan. 2015 ., №1 (35), p. 42-46
- Курбанов Р.Д., Абдуллаев Т.А. Амиркулов Б.Д. и соавт. Актуальные проблемы сердечной ресинхронизирующей терапии у больных с тяжелой формой ХСН //Кардиология Узбекистана. 2015. №3, С.79-85. Qurbanov R.D., Abdullaev T.A., Amirqulov B.D. and co-athours. Actual problems of cardiac resynchroniation therapy in patients with sevre chronic heart failure// Cardiology of Uzbekistan. 2015., №3-C, p. 79-85
- Мареев Ю. В., Мареев В. Ю. Характеристика и. течение пациентов с ХСН, юсиизализированных в стационар. Кардиология. 2017; 57 (S4):20-30. Mareev Y.V., Mareev V.Y. Characterization and treatment of patients with heart failure hospitalized in a hospital. Cardiology. 2017; 57 (S4):20-30.
- Поляков Д. С., Фомин И. В., Валикулова Ф. Ю. и др. Эпидемиологическая программа ЭПОХА – ХСН: декомпенсация хронической сердечной недостаточности в реальной клинической практике (ЭПОХА -Д – ХСН). Журнал Сердечная Недостаточность. 2016; 17 (5):299-305. Polyakov D.S., Fomin I.V., Vanikulova F.Y. and others. Epidemiological program EPOCH – CHF: decompensation of chronic heart failure in real clinical practice (EPOCH-D – CHF). Journal of Heart Failure. 2016; 17 (5):299-305.
- Резник Е.В. Особенности поражения органов-мишеней у болных с хронической сердечной недостаточностью. Диссертация на соискание ученой степене доктора медицинских наук-. Москва. 2016; 500 с. Reznik Y.V. Features of target organ damage in patients with chronic heart failure. The dissertation for the degree of Doctor of Medical Sciences. Moscow.2016; p. 500.
- Рекомендации ESC по диагностике и. течению острой и хронической сердечной недостаточности 2016 (избранные положения) //Лцки Украцни – Medicine of Ukraine. – 2016. – №78 (203-204). – С. 8-12. ESC recommendations for the diagnosis and treatment of acute and chronic heart failure 2016 (selected provisionsy/Лцки Украцни – Medicine of Ukraine. – 2016. – №7-8 (203-204). – С. 8-12.
- Рабочая группа по диагностике и. течению острой и хронической сердечной недостаточности Европейского Общества кардиологов (ESC) При участии: Ассоциации Сердечной Недостаточности (АСН) в составе ESC// Российский кардиологический журнал. -2017. – №1 (141). – С7-81. Working Group on the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) With the participation of: Association of Heart Failure (ASH) as part of ESC // Russian Journal of Cardiology. -2017. – №1 (141). – С7-81.
- Фомин И. В. Хроническая сердечная недостаточность в Российской Федерации: что сегодня мы знаем и что должны делать. Российский кардиологический журнал. 2016; (8):7-13. Fomin I.V. Chronic heart failure in the Russian Federation: what we know today and what we should do. Russian Journal of Cardiology.2016; (8):7-13.
- AlFaleh H, Elasfar AA, Ullah A, AlHabib KF, Hersi A, Mimish L et al. Worsening heart failure in “real-world” clinical practice: predictors and prognostic impact: WHF in “real-world” clinical practice. European Journal of Heart Failure. 2017; 19 (8):987-95.
- Damman K., Gori M., Claggett B. et al. Renal Effects and Associated Outcomes during Angiotensin-Neprilysin Inhibition in Heart Failure. JACC Heart Fail. 2018.
- ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2016 The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2016 of the European Society of Cardiology. Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. // Eur. Heart J. – 2016. – Vol. 10. – P. 1093-1128.
- Hoes MF, Grote Beverborg N, Kijlstra JD, Kuipers J, Swinkels DW, Giepmans BNG et al. Iron deficiency impairs contractility of human cardiomyocytes through decreased mitochondrial function: Impaired contractility in iron-deficient cardiomyocytes. European Journal of Heart Failure. 2018; 20 (5):910-9.
- Green JB, Bethel MA, Armstrong PW et al. Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes. New England Journal of Medicine. 2015; 373 (3):232-42.
- Lipska KJ. Metformin Use in Patients with Historical Contraindications. Annals of Internal Medicine. 2017;166 (3):225.
- Mant J, Doust J, Roalfe A, Barton P, Cowie M, Glasziou P et al. Systematic review and individual patient data meta-analysis of diagnosis of heart failure, with modelling of implications of different diagnostic strategies in primary care. Health Technology Assessment [Internet]. 2009 [cited on Febrary 1, 2018]; 13 (32).
- Preeti J., Alexandre M., Pupalan I. et al. Chronic Heart Failure and Comorbid Renal Dysfunction – A Focus on Type 2 Cardiorenal Syndrome. Curr Cardiol Rev. 2016; 12 (3): 186-94.
- Ponikowski P., A. Voors A., D. Anker S., et al. Рекомендации ESC по диагностике и лечению острой и хронической сердечной недостаточности 2016. Российский кардиологический журнал. 2017;(1):7-81
- Sen J., Chung E., McGill D. Tolvaptan for Heart Failure in Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis. Heart Lung Circ. 2018; 27 (8): 928-939.
- Whelton PK, Carey RM, Aronow WS, Casey DE, Collins KJ, Dennison Himmelfarb C et al. 2017 ACC / AHA / AAPA / ABC / ACPM / AGS / APhA / ASH / ASPC / NMA / PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. Journal of the American College of Cardiology. 2018;71 (19): e127-248.
- Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Colvin MM et al. 2017 ACC / AHA / HFSA Focused Update of the 2013 ACCF / AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology / American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Circulation. 2017;136 (6): e137-61.