43 -4 (32/1) 2020 — Kasimova M.S., Khamraeva G.Kh. — COMPLEX TREATMENT OF PATIENTS WITH OPTIC NEURITIS ON THE BACKGROUND OF MULTIPLE SCLEROSIS
COMPLEX TREATMENT OF PATIENTS WITH OPTIC NEURITIS ON THE BACKGROUND
OF MULTIPLE SCLEROSIS
Kasimova M.S. -Tashkent Institute of Postgraduate Medical Education, 100007 Uzbekistan Tashkent, Parkent 51
Khamraeva G.Kh. -Tashkent Institute of Postgraduate Medical Education, 100007 Uzbekistan Tashkent, Parkent 51
Resume
The aim of study was to analysis of the effectiveness of complex treatment of patients with optic neuritis (ON) due to multiple sclerosis (MS). Depending on the type of treatment, patients with ON due to MS were divided into 2 groups: in the first (main) group (26 patients, 42 eyes), complex treatment was used with the addition of drugs modifying the course of MS. In the second (control) group (18 patients, 27 eyes), only traditional treatment was used. Traditional treatments have included anti-inflammatory, decongestant, and desensitizing therapies. The inclusion of drugs modifying the course of MS in the complex treatment of ON against the background of MS made it possible to increase visual acuity by 1.74 times, expand the field of view by 1.42, and reduce the latency of VEP by 6.7%.
Keywords: optic neuritis, multiple sclerosis, treatment, Glatiramer acetate.
First page
186
Last page
188
For citation: Kasimova M.S., Khamraeva G.Kh. Complex treatment of patients with optic neuritis on the background of multiple sclerosis//New Day in Medicine 4(32)2020 186-188 https://cutt.ly/Gl4BS8A
List of References
- Zamyatina E.A. The effect of copaxone on the clinical manifestations and condition of other inflammatory demyelinating diseases of the central nervous system // Neurological journal. – 2015; 20 (6): 4-9.
- Skripchenko N.V., Ivanova G.P., Surovtseva A.V. Complex therapy of multiple sclerosis in children. Russian Bulletin of Perinatology and Pediatrics. – 2016, 2:61-67.
- Schmidt T.E. Pathogenetic treatment of multiple sclerosis. Medical advice journal. – 2010; 9: 74-79.
- Kamilov H.M., Kasimova M.S., Khamraeva G.H. Diagnostic Value of the Visual Evoked Potential Investigation in Optic Neuritis. International Journal of Biomedicine. – 2015, 3: 147-150.
- Kamilov H.M., Kasimova M.S., Khamraeva G.Kh. Mor- phofunctional methods for assessing the dynamics of optic neuritis. National Journal of Glaucoma. – 2017; 16:37-42.
- Khamraeva G.Kh. Analysis of the results of the study of visual evoked potentials depending on the stage of optic neuritis. The Eye. – 2017; 3:32-36.
- Kasimova M.S., Khamraeva G.H. Status of Morphometric Parameters of the Fundus in Optic Neuritis Due to Devic’s Neuromyelitis Optica. American Journal of Medicine and Medical Sciences. – 2020, 10(10): 826-832. DOI: 10.5923/j.ajmms.20201010.20
- Morrow MJ, Ko MW. Should oral corticosteroids be used to treat demyelinating optic neuritis? J Neuroophthalmol. – 2017;37:444- 450.
- Morrow SA, Fraser JA, Day C, Bowman D, Rosehart H, Kremenchutzky M, Nicolle M. Effect of treating acute optic neuritis with bioequivalent oral vs intravenous corticosteroids: a randomized clinical trial. JAMA Neurol. – 2018; 75:690-696.
- Nolan R.C., et al. Evolution of Visual Outcomes in Clinical Trials for Multiple Sclerosis Disease-Modifying Therapies. J Neuroophthalmol. – 2018; 38(2): 202-209.
- Sarah A. Morrow, J. Alexander Fraser, Chad Day et all, Effect of Treating Acute Optic Neuritis With Bioequivalent Oral vs Intravenous Corticosteroids. A Randomized Clinical Trial // JAMA Neurol. – 2018; 75(6): 690-696.