104 -5 (67) 2024 - Safarova G.A. - CLINICAL FEATURES OF NEPHROPATHY IN POST-COVID SYNDROME

CLINICAL FEATURES OF NEPHROPATHY IN POST-COVID SYNDROME

Safarova G.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Coronavirus infection is dangerous not only by inflammation and lesions of the lung tissue. Complications of the disease, carried in any form, affect the heart, brain and kidneys. The urinary system is affected in 59% of all cases of complications. Objective. To study clinical peculiarities of renal diseases in patients in the post-covid period. Materials and methods of research: 60 patients diagnosed with COVID-19 in anamnesis were included in the study. Results: When studying the history of the patients, a specific clinical picture of nephropathies in patients in the post-covid period was revealed. A comparative analysis of clinical and laboratory data revealed predominantly proteinuria, hematuria and decreased SCF, indicating a significantly worse prognosis of the disease. Conclusions: SARS-CoV-2 virus directly or indirectly affects the kidneys. The impairment of function and morphology of previously healthy kidneys observed in COVID-19 infection is reversible in most cases. Renal damage scores in COVID-19 infection are associated with a worse prognosis.

Key words: COVID-19, clinical features of nephropathy, post-Covid renal syndrome.

First page

604

Last page

608

For citation:Safarova G.A. - CLINICAL FEATURES OF NEPHROPATHY IN POST-COVID SYNDROME//New Day in Medicine 5(67)2024 604-608 https://newdayworldmedicine.com/en/article/3758

List of References

  1. Zhou F., Yu T., Du R. et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395: 1054-62.
  2. Hassanein M, Radhakrishnan Y, Sedor J, Vachharajani T, Vachharajani VT, Augustine J, Demirjian S, Thomas G. COVID-19 and the kidney. Cleve Clin J Med. 2020 Oct 1;87(10):619-631. doi: 10.3949/ccjm.87a.20072. PMID: 33004323.
  3. Novel Evidence of Acute Kidney Injury in COVID-19 / T. I. Chute [et al.] // J. Clin. Med. – 2020 Nov. – Vol. 9, N 11. – P.3547.
  4. Varga, Z. et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet 2020, 395, 1417–1418.
  5. SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule / A. Werion [et al.] // Kidney Int. – 2020 Nov. – Vol. 98, N 5. – P. 1296–1307
  6. Патологическая анатомия COVID-19: Атлас / Зайратьянц О. В., Cамсонова М. В., Михалева Л. М., и соавт. – Москва, ГБУ «НИИОЗММ ДЗМ», 2020. – 140 с.
  7. Features of the indices of the resistance index of vasorenal vessels in monitoring the progression of chronic kidney disease. Safarova Gulnoz Avazkhonovna, Mukhamedjanova Mastura Khayatovna, Ubaydova Dilafruz Saddikovna. Asian journal of Pharmaceutical and biological research 2231-2218 http://www.ajpbr.org/ Volume 10. Issue 2. MAY-AUG 2021. 10.5281/zenodo.5519192 Pages 78-84
  8. Vasorenal hemodynamic changes in patients with chronic kidney disease in comorbidity with hypertonic disease. Safarova G.A. Asian journal of Pharmaceutical and biological research 2231-2218 http://www.ajpbr.org/ Volume 10. Issue 2. MAY-AUG 2021 10.5281/zenodo.5464135 Page 66-71.
  9. Mukhamedzhanova M.K., Safarova G.A. Assessment of vasorenal hemodynamics in patients with chronic kidney disease in association with arterial hypertension. Problems of Biology and Medicine 2020, No. 6 (124) 87-90 pp. UDC: 616.1+615.2.03+613.1
  10. Safarova G.A., Mukhamedjanova M.K., Ubaydova D. S. Features of the indices of the resistance index of vasorenal vessels in monitoring the progression of chronic kidney disease. Asian journal of Pharmaceutical and biological research 2231-2218 http://www.ajpbr.org/Volume 10. Issue 2. MAY-AUG 2021. 10.5281/zenodo.5519192 Pages 78-84
  11. Safarova GA Vasorenal hemodynamic changes in patients with chronic kidney disease in comorbidity with hypertonic disease. Asian journal of Pharmaceutical and biological research 2231-2218http://www.ajpbr.org/Volume 10. Issue 2. MAY-AUG 2021 10.5281/zenodo.5464135 Page 66-71.
  12. Safarova G.A., Shadzhanova N.S. The problem of nephropathy development in patients hospitalized with coronavirus infection // Asian journal of Pharmaceutical and biological research 2231-2218 http://www.ajpbr.org/ Universal IMPACT factor 7 SJIF 2022: 4.465 Volume 11 Issue 3 P. 62-67
  13. Safarova G.A., FEATURES OF THE ETIOLOGY AND MECHANISM OF KIDNEY DAMAGE IN PATIENTS WITH COVID-19. Asian journal of Pharmaceutical and biological research 2231-2218 http://www.ajpbr.org/ Universal IMPACT factor 7 SJIF 2022: 4.465 Volume 11 Issue 3 SEPT.-DEC. 2022 Page 68-71

    file

    download