110 -12 (74) 2024 - Kim Irina Leonidovna - MORPHOLOGICAL MANIFESTATIONS OF MICROELEMENTOSIS (LACK OF TRACE ELEMENTS) IN THE HEART
MORPHOLOGICAL MANIFESTATIONS OF MICROELEMENTOSIS (LACK OF TRACE ELEMENTS) IN THE HEART
Kim Irina Leonidovna - Bukhara State Medical Institute named after Abu Ali ibn Sina
Resume
The article is devoted to the study of morphological manifestations of microelementosis, especially in the context of the cardiovascular system. Trace elements such as magnesium, zinc, selenium and iron play a key role in maintaining normal heart function and structure. The lack of these trace elements leads to various pathological changes, including myocardial hypertrophy, inflammatory processes and cardiomyopathy. The paper examines the mechanisms through which micronutrient deficiency affects the morphology of the heart, as well as the clinical manifestations of these changes. Special attention is paid to the symptoms, diagnosis and prevention of micronutrient deficiency, which emphasizes the importance of their sufficient level to maintain the health of the cardiovascular system. The conclusion of the article focuses on the need for further research in this area in order to better understand the relationship between trace elements and morphological changes in the heart, as well as to develop effective strategies for the prevention and correction of micronutrient deficiency
Key words: microelementosis, white mongrel rats, morphology of the heart, magnesium, selenium, zinc
First page
579
Last page
585
For citation:Kim Irina Leonidovna - MORPHOLOGICAL MANIFESTATIONS OF MICROELEMENTOSIS (LACK OF TRACE ELEMENTS) IN THE HEART//New Day in Medicine 12(74)2024 579-585 https://https://newdayworldmedicine.com/en/new_day_medicine/12-74-2024
List of References
- Nieschlag E, Behre HM. Andrology: male reproductive health and dysfunction.-Berlin: Heidelberg, 2010.
- Geens T, Neels H, Covaci A. Distribution of bisphenol-A, triclosan and n-nonylphenol in human adipose tissue, liver and brain. Chemosphere. 2012;87(7):796-802.
- Hond ED, Tournaye H, Sutter PD, Ombelet W, Baeyens W, Covaci A, Cox B, Nawrot TS, Larebeke NV, D'Hooghe T. Human exposure to endocrine disrupting chemicals and fertility: A case-control study in male subfertility patients. Environment International. 2015;8(4):154-160.
- Li X, Ying G, Zhao J, Chen Z, Lai H, Su H. 4-Nonylphenol, bisphenol-A and triclosan levels in human urine of children and students in China, and the effects of drinking these bottled materials on the levels. Environment International. 2013;5(2):81-86.
- Pirard C, Sagot C, Deville M, Dubois N, Charlier C. Urinary levels of bisphenol A, triclosan and 4-nonylphenol in a general Belgian population. Environment International. 2012;48:78-83.
- Watanabe S., Wang R.-S., Miyagawa M., Kobayashi, Suda M., Sekiguchi S., Honma T. Disbalans urovnej testosterona u samcov potomkov krys, podvergavshihsya vozdejstviyu bisfenola A v perinatal'nyj period// Promyshlennoe zdorov'e.- 2003.- T. 41.- S. 338-341.
- Salian S, Doshi T, Vanage G. Neonatal exposure of male rats to bisphenol A impairs fertility and expression of Sertoli cell junctional proteins in the testis. Toxicology. 2009;2(65):56-67.
- Liu C, Duan W, Li R, Xu S, Zhang L, Chen C, He M, Lu Y, Wu H, Pi H, Luo X, Zhang Y, Zhong M, Yu Z, Zhou Z. Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity. Cell Death Dis. 2013;4(5):676.
- Qiu L.L, Wang X, Zhang X.H, Zhang Z, Gu J, Liu L, Wang Y, Wang X, Wang S.L. Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A. Toxicol Lett. 2013;2(19):116-124.
- Kumar V, Chakraborty A, Kural M, Roy P. Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan. Reprod Toxicol. 2009;2(7):177-185. http://dx.doi.org/ 10.1016/j.reprotox.2008.12.002.
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