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  • 99 -1 (75) 2025 - Oblokulov A.A. - PRIMARY PROPHYLAXIS OF SPONTANEOUS BACTERIAL PERITONITIS IN LIVER CIRRHOSIS OF VIRUS ETIOLOGY

99 -1 (75) 2025 - Oblokulov A.A. - PRIMARY PROPHYLAXIS OF SPONTANEOUS BACTERIAL PERITONITIS IN LIVER CIRRHOSIS OF VIRUS ETIOLOGY

PRIMARY PROPHYLAXIS OF SPONTANEOUS BACTERIAL PERITONITIS IN LIVER CIRRHOSIS OF VIRUS ETIOLOGY

Oblokulov A.A. - Bukhara State Medical Institute named after Abu Ali ibn Sino

Resume

The clinical and laboratorical characteristics of spontaneous bacterial peritonitis with cirrhosis of the liver of viral etiology were studied. A total of 58 (32 (55.2%) men and 26 (40.6%) women) patients with cirrhosis of the liver of viral etiology aged 30 to 69 years were examined. Upon admission, all patients underwent diagnostic laparocentesis, followed by counting the number of neutrophils in the AF and plating on culture media. It was established in the examined patients that cirrhosis with HCV markers was most frequently encountered. An analysis of the infection factors in the examined patients with liver cirrhosis with complicated SBP showed that problems associated with parenteral interventions were noted by 67.3% and the source of infection was not established in 24.1% of patients. The most common signs of SBP were dyspeptic symptoms-60.3%, fever-37.9%, leukocytosis with the appearance of immature forms of leukocytes-48.2%.

Key words: Spontaneous bacterial peritonitis (SBP), cirrhosis, laparocentesis, ascetic fluid.

First page

573

Last page

576

For citation:Oblokulov A.A. - PRIMARY PROPHYLAXIS OF SPONTANEOUS BACTERIAL PERITONITIS IN LIVER CIRRHOSIS OF VIRUS ETIOLOGY//New Day in Medicine 1(75)2025 573-576 https://https://newdayworldmedicine.com/en/new_day_medicine/1-75-2025

List of References

  1. Conn H.O. Spontaneous peritonitis and bacteremia in Laennec’s cirrhosis caused by enteric organisms. A relatively common but rarely recognized syndrome //Ann. Intern. Med. 1964;60:568-5802.
  2. Винницкая Е.В., Осипов Г.А., Дроздов В.Н. и др. Диагностика спонтанного бактериального перитонита при циррозе печени //Экспериментальная и клиническая гастроэнтерология. 2008;3:18-24.
  3. Jepsen P. et al. Prognosis of patients with liver cirrhosis and spontaneous bacterial peritonitis //Hepatogastroenterology. 2003;50:2133-2136.
  4. Merino Rodriguez B. et al. Prognostic value of a spontaneous bacterial peritonitis episode in cirrhotic patients in clinical practice //Gastroenterol. Hepatol. 2008;31(9):560-565.
  5. Бондаренко В.М., Воробъев А. А. Дисбиозы и препараты с пробиотической функцией //Журн. Микробиол. 2004;1:84-92.
  6. Ghassemi S., Garsia-Tsao G. Prevention and treatment of infections in patients with cirrhosis //Best Pract. Res. Clin. Gastroenterol. 2007;21(1):77-93.
  7. Облокулов А.Р., Нарзиев И.И., Абдуллаев Т.У., Облокулов А.А. ВГВ лямблиоз билан кечган микс инфекцияда аллергик кўрсаткичларнинг аҳамияти //Тиббиётда янги кун. 2018;2(22):101-104. https://newdayworldmedicine.com/en/article/85
  8. Белобордова Н.В., Осипов Г.А. Гомеостаз малых молекул микробного происхождения и его роль взаимоотношениях микроорганизмов с хозяином //Вестник РАМН. 1999;16(7):25-31.
  9. Ong HS, Kang CI, Lee JA et al. Clinical significance and outcome of nosocomial acquisition of spontaneous bacterial peritonitis in patients with liver cirrhosis. //Clin Infest Dis. 2009;48(9):1230-1236.
  10. D’Amico G., Garsia-Tsao G., Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. //J Hepatol. 2006;44(1):217-231.
  11. Mukhammadieva M.I. (2022). Modern Clinical and Biochemical Characteristics of Liver Cirrhosis Patients of Viral Etiology with Spontaneous Bacterial Peritonitis //Texas Journal of Medical Science. 2022; 86-90 pp.
  12. Mukhammadieva M.I. (2023). Вирус этиологияли жигар циррози беморларида спонтан бактериал перитонит билан асоратланишнинг профилактикаси ва давосини такомиллаштириш //Oriental Renaissance: Innovative, educational, natural and social sciences. 2023; 947-953 pp.
  13. Sanokulova Sitora Avazovna. (2023). Acute Kidney Injury in Critically Ill Cirrhotic Patients with Spontaneous Bacterial Peritonitis. //Texas Journal of Medical Science, 2023;25:65-70.
  14. Oblokulov A.R., M.I. Mukhammadieva. (2022). Clinical and biochemical characteristics of liver cirrhosis patients of viral etiology with spontaneous bacterial peritonitis //Academicia Globe: Indersciense Research. 2022; 210-216 pp.
  15. Облоқулов А.Р., Муҳаммадиева М.И. (2022). Клинико-лабораторная характеристика спонтанного бактериального перитонита при циррозе печени вирусной этиологиии. //Журнал вестник врача 2022;1(3):66-69.

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