107 -2 (76) 2025 - Musashaykhov U.Kh., Aripov O.A. - PROGNOSTIC SIGNIFICANCE OF VEGFA GENE POLYMORPHISM IN PREDICTING THE DEVELOPMENT OF CHRONIC HEART FAILURE

PROGNOSTIC SIGNIFICANCE OF VEGFA GENE POLYMORPHISM IN PREDICTING THE DEVELOPMENT OF CHRONIC HEART FAILURE

Musashaykhov U.Kh. - Andijan State Medical Institute

Aripov O.A. - Center for the Development of Professional Qualifications of Medical Workers under the Ministry of Health of the Republic of Uzbekistan

Boboyev K.T. - Republican Specialized Scientific and Practical Medical Hematology Center

Musashaykhova Sh.M. - Andijan State Medical Institute

Мakhsudov O.M. - Andijan State Medical Institute

Resume

In patients with chronic heart failure (CHF) suffering from ischemic heart disease (IHD), a study was conducted to analyze the distribution of the C-634G polymorphic marker in the VEGFA gene to predict CHF. The main group consisted of 103 patients, and the control group included 105 "conditionally healthy" individuals. Clinical and laboratory investigations were conducted at the Republican Specialized Scientific-Practical Hematology Center of the Ministry of Health of the Republic of Uzbekistan. The VEGFA polymorphism was studied using the commercial test kit from Synthol LLC (Russia) on the Rotor-Gene Q (Quagen, Germany) device.

Keywords: C-634G polymorphism, VEGFA genetic marker, CHF, IHD.

First page

604

Last page

607

For citation:Musashaykhov U.Kh., Aripov O.A., Boboyev K.T., Musashaykhova Sh.M., Мakhsudov O.M. - PROGNOSTIC SIGNIFICANCE OF VEGFA GENE POLYMORPHISM IN PREDICTING THE DEVELOPMENT OF CHRONIC HEART FAILURE//New Day in Medicine 2(76)2025 604-607 https://https://newdayworldmedicine.com/en/new_day_medicine/2-76-2025

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