102 -6 (80) 2025 - H.K.Muxtorova, M.B.Istamov - CLINICAL AND DYNAMIC FEATURES OF DEPRESSIVE DISORDERS IN TYPE II DIABETES MELLITUS

CLINICAL AND DYNAMIC FEATURES OF DEPRESSIVE DISORDERS IN TYPE II DIABETES MELLITUS

H.K.Muxtorova - Bukhara State Medical Institute named after Abu Ali ibn Sina

M.B.Istamov - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This article analyzes the clinical and dynamic features of depressive disorders in patients with Type II diabetes mellitus. Depression is a common psychological condition in these patients, which may exacerbate disease complications and negatively affect treatment outcomes. The article examines the symptomatic manifestations of depressive disorders, their progression, and variability related to the course of the disease. Additionally, the clinical presentation of depression in Type II diabetes, its etiopathogenesis, and its impact on patients’ quality of life and social functioning are studied. The content is based on recent research and literature reviews, ъhighlighting the complex nature of the disease and the significance of psychological factors

Keywords: Type II diabetes mellitus, depressive disorders, clinical features, dynamic features, psychological state, etiopathogenesis, quality of life, disease complications

First page

500

Last page

502

For citation:H.K.Muxtorova, M.B.Istamov - CLINICAL AND DYNAMIC FEATURES OF DEPRESSIVE DISORDERS IN TYPE II DIABETES MELLITUS//New Day in Medicine 6(80)2025 500-502 https://newdayworldmedicine.com/en/new_day_medicine/6-80-2025

List of References

1. IDF Diabetes Atlas. 10th edition. International Diabetes Federation, 2021.
2. Mezuk B, Eaton W.W., Albrecht S, Golden S.H. Depression and Type 2 Diabetes Over the Lifespan: A Meta-analysis. Diabetes Care. 2008;31(12):2383-2390.
3. Golden S.H., Lazo M, Carnethon M, et al. Examining a bidirectional association between depressive symptoms and diabetes. JAMA. 2008;299(23):2751-2759.
4. Moulton C.D., Pickup J.C., Ismail K. The link between depression and diabetes: the search for shared mechanisms. Lancet Diabetes Endocrinol. 2015;3(6):461-471.
5. Pan A, Lucas M, Sun Q, et al. Bidirectional association between depression and type 2 diabetes mellitus in women. Arch Intern Med. 2010;170(21):1884-1891.
6. Dowlati Y, Herrmann N, Swardfager W, et al. A meta-analysis of cytokines in major depression. Biol Psychiatry. 2010;67(5):446-457.
7. Lustman P.J., Clouse R.E. Depression in diabetic patients: the relationship between mood and glycemic control. J Diabetes Complications. 2005;19(2):113-122.
8. Katon W, von Korff M, Lin E.H., et al. Behavioral and clinical factors associated with depression among individuals with diabetes. Diabetes Care. 2004;27(4):914-920.
9. Gonzalez J.S., Peyrot M, Mc Carl L.A., et al. Depression and diabetes treatment nonadherence: a meta-analysis. Diabetes Care. 2008;31(12):2398-2403.
10. Fisher L, Glasgow R.E., Mullan J.T., et al. Development of a brief diabetes distress screening instrument. Ann Fam Med. 2008;6(3):246-252.
11. Bogner H.R., de Vries H.F., Morales K.H., et al. Integrated management of type 2 diabetes and depression treatment to improve medication adherence: a randomized controlled trial. Ann Fam Med. 2012;10(1):15-23.
12. Lustman P.J., Anderson R.J., Freedland K.E., et al. Depression and poor glycemic control: a meta-analytic review of the literature. Diabetes Care. 2000;23(7):934-942.
13. Raison C.L., Miller A.H. Depression in cancer: new developments regarding diagnosis and treatment. Biol Psychiatry. 2011;70(3):249-250.

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