34 -7 (81) 2025 - Sabirov U.Yu., Yakubov A.A. - EFFECTIVENESS OF ROSACEA THERAPY TAKING INTO ACCOUNT GLUTATHIONE-S-TRANSFERASE INDICATORS
EFFECTIVENESS OF ROSACEA THERAPY TAKING INTO ACCOUNT GLUTATHIONE-S-TRANSFERASE INDICATORS
Sabirov U.Yu. - Republican Specialized Scientific and Practical Center for Dermatovenereology and Cosmetology Uzbekistan
Yakubov A.A. - Republican Specialized Scientific and Practical Center for Dermatovenereology and Cosmetology Uzbekistan
Resume
Rosacea is a multifactorial chronic inflammatory disease mainly of the skin of the face of a non—infectious nature, which is characterized by the development of erythema, telangiectasia, papules, pustules, eye damage, and the formation of rhinophyma, prone to progression. The main purpose of glutathione S-transferase (GST) enzymes is to neutralize electrophilic compounds formed, in particular, during oxidative stress. Glutathione-S-transferases are a large group of isoenzymes with diverse functional activity and play an important role in detoxification of the body by various mechanisms. The variety of treatment methods for rosacea is explained by the complex etiopathogenetic picture of the disease, and the variability of the stages and clinical forms of dermatosis further complicates the task of choosing an adequate therapy.
Key words: rosacea, antioxidant system, glutaredox, glutathione S-transferase, rosacea treatment.
First page
174
Last page
177
For citation:Sabirov U.Yu., Yakubov A.A. - EFFECTIVENESS OF ROSACEA THERAPY TAKING INTO ACCOUNT GLUTATHIONE-S-TRANSFERASE INDICATORS//New Day in Medicine 7(81)2025 174-177 https://newdayworldmedicine.com/en/new_day_medicine/7-81-2025
List of References
- Rolleston J. D. A. Note on the Early History of Rosacea. Proc R Soc Med 1933; 26 (4): 327—329 ttps://www.who.int/publications/i/item/9789240110496/
- Chauhan N. Rosacea: patophyziology and management principles / N. Chauhan, D.A. Ellis // Facsial Plast. Surg. Clin. North Am. – 2013. – Vol. 21, № l. – P.127-136.
- Котельникова М.А., Симонова Н.В., Меньщикова Н.В., Штарберг М.А. /Результаты исследования параметров психоэмоционального и антиоксидантного статуса у больных розацеа. Медицинский вестник Башкортостана. 2017.Том 12, № 5(71) dr.abdulaziz1985@icloud.com
file
download