36 -8 (82) 2025 - Yuldashev K.Sh., Mahkamov N.J. - COMPARATIVE MORPHOLOGICAL ANALYSIS OF POST-TRAUMATIC POLYPOSIS RHINOSINUSITIS ACROSS DIFFERENT AGE GROUPS

COMPARATIVE MORPHOLOGICAL ANALYSIS OF POST-TRAUMATIC POLYPOSIS RHINOSINUSITIS ACROSS DIFFERENT AGE GROUPS

Yuldashev K.Sh. - Fergana Medical Institute of Public Health

Mahkamov N.J. - Andijan State Medical Institute

Resume

This study presents a comparative analysis of mucosal tissue pathomorphological changes in post-traumatic polyposis rhinosinusitis across different age groups. Morphological examination was performed using hematoxylin–eosin and Masson’s trichrome staining techniques. Age-related comparative results revealed significant differences in the degree of inflammatory infiltration, microcirculatory alterations in blood vessels, and the intensity of stromal fibrosis. These findings morphologically confirm the impact of age on tissue regenerative capacity and the progression of the fibrotic process.

Keywords: post-traumatic polyposis rhinosinusitis, age groups, morphology, inflammatory infiltration, fibrosis.

First page

204

Last page

209

For citation:Yuldashev K.Sh., Mahkamov N.J. - COMPARATIVE MORPHOLOGICAL ANALYSIS OF POST-TRAUMATIC POLYPOSIS RHINOSINUSITIS ACROSS DIFFERENT AGE GROUPS//New Day in Medicine 8(82)2025 204-209 https://newdayworldmedicine.com/en/new_day_medicine/8-82-2025

List of References

  1. Fiorentino et al., “The Morphology of Nasal Polyps in Different Age Groups: Histopathological Features,” Journal of Personalized Medicine, 2024;14(4):414–430. DOI:10.3390/jpm14040414. 414–430. MDPI
  2. Fiorentino et al., “Age-related morphological features of nasal polyps,” SIAPeCMDP, 2023; pp. bohrium.com
  3. Chan et al., “Chronic Rhinosinusitis with Nasal Polyps: Age and Disease Severity,” Medicina (MDPI), 2022;57(3):282–295. 282–295. PMC
  4. Brown et al., “Histopathologic differences between adult and pediatric patients with chronic rhinosinusitis,” International Forum of Allergy & Rhinology, 2022;13(2):200–210. DOI:10.1002/alr.23037. 200–210. ResearchGate
  5. Coffinet et al., “Immunopathology of Chronic Rhinosinusitis in Young Children,” Otolaryngology–Head and Neck Surgery, 2009;140(5):708–714. 708–714. ResearchGate
  6. ScienceDirect study on pediatric prevalence, “Histological analysis of nasal polyps in children,” Pediatric Otolaryngology, 2001;5(4):215–220. 215–220. ScienceDirect
  7. Chauhan & Ranjan, “Nasal polyps and its histopathological classification,” Asian Journal of Medical Sciences, 2023;14(8):166–172. 166–172. Semantic Scholar
  8. Fiocchi et al., “Endotypes of Nasal Polyps in Children: A Multidisciplinary Approach,” Journal of Personalized Medicine, 2023;13(5):707–720. DOI:10.3390/jpm13050707. 707–720. MDPI
  9. Prevalence data, “Prevalence and histopathology of chronic polypoid sinusitis” (ScienceDirect), 2011;19(6):455–460. 455–460. ScienceDirect
  10. EPOS 2020, European Position Paper on Rhinosinusitis and Nasal Polyps, Supplement to Rhinology Journal, 2020; Suppl.29, pp. 1–64. Rhinology Journal
  11. Historical overview, "A short history of nasal polyposis," Respiratory History Quarterly, 2023;12(2):50–57. 50–57. ScienceDirect

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