22 -2 (40) 2022 — Urmanova Yu.M., Mavlonov U.Kh. — EFFECTIVENESS OF THERAPY WITH THYROID DRUGS IN ADOLESCENTS WITH DELAYED PUBERT

EFFECTIVENESS OF THERAPY WITH THYROID DRUGS IN ADOLESCENTS WITH DELAYED PUBERT

Urmanova Yu.M., Tashkent Pediatric Medical Institute, Bukhara Endocrinological Dispensary,Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Tashkent, Uzbekistan

Mavlonov U.Kh., Tashkent Pediatric Medical Institute, Bukhara Endocrinological Dispensary,Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Tashkent, Uzbekistan

Alieva D.A., Tashkent Pediatric Medical Institute, Bukhara Endocrinological Dispensary,Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Tashkent, Uzbekistan

Dalimova G.A., Tashkent Pediatric Medical Institute, Bukhara Endocrinological Dispensary,Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Tashkent, Uzbekistan

Safarova Sh.M., Tashkent Pediatric Medical Institute, Bukhara Endocrinological Dispensary,Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Tashkent, Uzbekistan

Savchuk D.V. Tashkent Pediatric Medical Institute, Bukhara Endocrinological Dispensary,Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after acad. Y.H. Turakulova, Tashkent, Uzbekistan

Resume

After 3, 6 months after the treatment of thyroid gland in dynamics in patients with a delay of puberty and iodine deficiency illness (DP + YDI), a reliable improvement in hormonal indicators was observed, namely the mean values of TSH, free T4 (P <0.005) .If growth rate in patients DP + YDI before treatment was 3.3 ± 0.2 cm / year, after 6 months of treatment with thyroid glands, averaged 6.4 ± 0.3 cm / year (6.5-9.8 cm / year ), and an absolute increase in growth in 6 months averages amounted to: 8.4 ± 0.4 cm. Thus, on the basis of a study, it can be concluded that therapy of thyroid glands in patients with DP + YDI helps a reliable improvement of both hormonal, so and anthropometric indicators, which confirms the need for the primary prevention of  YDI  among children and adolescents.

Key words: delay of puberty, teenagers, iodine deficiency illness

First page

107

Last page

112

For citation: Urmanova Yu.M., Mavlonov U.Kh., Alieva D.A., Dalimova G.A., Safarova Sh.M., Savchuk D.V. EFFECTIVENESS OF THERAPY WITH THYROID DRUGS IN ADOLESCENTS WITH DELAYED PUBERT //New Day in Medicine 2(40)2022 107-112 https://cutt.ly/mAkhFCb

LIST OF REFERENCES:

  1. Боборыкина А.Е. Клиническое значение дефицита йода для здоровья детей раннего и дошкольного возраста // Пермский медицинский журнал. 2006. – Т23, №6. -С.125-133
  2. Бруно Де Бенуа. Устранение дефицита йода — одна из ключевых задач здравоохранения. //Международный эндокринологический журнал Донецк, 6 (38) 2011, стр 12-18.
  3. Шабалов Н.П. Диагностика и лечение эндокринных заболеваний у детей и подростков//М., 2009г, 527 стр. 
  4. Шубина Е.В.  Особенности зобной эндемии в условиях крупного промышленного города // Материалы Всероссийского семинара «Современные проблемы поликлинической педиатрии». Москва, 4-16 февраля 2002г. -М. 2002. -C.l08-114
  5. Фадеев В.В. Нормативы уровня ТТГ: нужны ли изменения?  // Клиническая тиреоидология. 2004. – Т.2, № 3. -С. 5- 9
  6. Фадеев В.В. Профессиональный взгляд на проблему гипотиреоза   // Лечащий врач. 2005. – №5. – С. 26 -29
  7. Col N.F. Subclinical thyroid disease: clinical applications   // JAMA. 2004. – Vol.291. – P. 239-243
  8. De Groote P, Baert J, Carpentier P, Fonteyne E, Morelle V. Service d’Urologie, Onze Lieve Vrouw Ziekenhuis, Aalst. Antegrade scrotal sclerotherapy in the treatment of varicocele.// Acta Urol Belg;1995;5;63(2);57 -62
  9. Mitchell D.R. Rules-based detection of discrepancies between TSH and free T4 results   // Clinical Chime Acta. 2003. – Vol.332. – P. 89 -84
  10. Thompson C. Dietary recommendations for iodine around the world   // IDD Newsletter. 2002. – V108. – №3. – P. 38-42
  11. Toft A. Thyroid hormone treatment, holy and when?   // Thyroid international. 2001. – №4. – P. 12-15
  12. Zimmermann M.B. Iron Status influences the efficacy of iodine prophylaxis in goitrous children in Cote d’lvoire   // Into Journal Vitamin. Res. — 2002. — Vol.72. — P. 19-25
  13. De Sanctis V, Urso L, Malagutti L. Clinical and ultrasound follow-up of epididymis cysts in adolescence.// Minerva Pediatr. 2001 0ct;53(5):510 -1
  14. Mavlonov U.Kh., Aliyeva D.A., Urmanova Yu.M., Dalimova G.A” The frequency of the delay of puberty and various developmental disorders  in adolescents in Namangan and Jizzakh regions of the Republic of Uzbekistan on the data of screening in 2021 year“// Biomedical Journal of scientific and technical research. ISSN: 2574 -1241 , Volume 38- Issue 1  pg  29926  – 29929      DOI: 10.26717/BJSTR.2021.38.006080

file

download