87 -10 (84) 2025 - Bakhshilloeva R.E., Rakhmatov O.B. - METHODS FOR IDENTIFYING TORCH INFECTION AGENTS IN VITILIGO PATIENTS

METHODS FOR IDENTIFYING TORCH INFECTION AGENTS IN VITILIGO PATIENTS

Bakhshilloeva R.E. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Rakhmatov O.B. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

This article discusses specific methods for identifying TORCH pathogens that are important in the clinical course of vitiligo. Clinical changes that can occur in patients with secondary immunodeficiency due to pathogen activity were also observed in patients. The scientific analysis examined the frequency of white spots in this group of vitiligo patients, their instability, and resistance to traditional treatment methods. From a scientific and practical perspective, the value of clinical and laboratory parameters as prognostic risk factors in the diagnosis of TORCH pathogens as a comorbidity in patients with vitiligo is examined.

Keywords: vitiligo, repigmentation, TORCH infection, humoral immunity, herpes simplex virus I and II, cytomegalovirus

First page

506

Last page

511

For citation:Bakhshilloeva R.E., Rakhmatov O.B. - METHODS FOR IDENTIFYING TORCH INFECTION AGENTS IN VITILIGO PATIENTS//New Day in Medicine 10(84)2025 506-511 https://newdayworldmedicine.com/en/new_day_medicine/10-84-2025

List of References

  1. Арифов С.С. Роль индивидуальных особенностей организма в клиническом течении, патогенезе витилиго и разработка комплексного метода лечения: Дис. … д–ра мед. наук. – Ташкент, 1994; 299 стр.
  2. Bibeau K et al. Mental health and psychosocial quality-of-life burden among patients with vitiligo: findings from the global VALIANT study. // JAMA Dermatol. 2023;159(10):1124-28.
  3. Yadav, Amit. (2019). Histopathology and Molecular Pathology of Vitiligo. 10.5772/intechopen.84258.
  4. Kruger C, Schallreuter KU (2012) A review of the worldwide prevalence of vitiligo in children/adolescents and adults. // Int J Dermatol 2012;51(10):1206-1212.
  5. Li JX, Yu TS, Hsu SB, Lin HJ, Tsai FJ. Association of herpes simplex virus infection and vitiligo: a nationwide retrospective cohort study. Arch Dermatol Res. 2024 Dec 9;317(1):90. doi: 10.1007/s00403-024-03612-x. PMID: 39652192.
  6. Akbayir N, Gokdemir G, Mansur T, Sokmen M, Gunduz S, Alkim C et al (2004) Is there any relationship between hepatitis C virus and vitiligo? // J Clin Gastroenterol 38(9):815–817.
  7. Lucchese G (2019) Herpesviruses, autoimmunity and epilepsy: peptide sharing and potential cross-reactivity with human synaptic proteins. // Autoimmun Rev 2019;18(10):102367
  8. Ribeiro RPS, Lacerda KAP, Guillo LA (2023) Analysis of serum immunoglobulin G (IgG) levels against Toxoplasma Gondii, herpes Simplex Virus types 1 and 2, Cytomegalovirus and Hepatitis C Virus in Vitiligo. // Indian J Dermatol 2023;68(5):588.

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