111 -10 (84) 2025 - Akhmatova G.R. - INFLUENCE OF HIGH-ONCOGENIC VIRUSES ON BREAST CANCER DEVELOPMENT

INFLUENCE OF HIGH-ONCOGENIC VIRUSES ON BREAST CANCER DEVELOPMENT

Akhmatova G.R. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Breast cancer is one of the most common oncological diseases among women. In recent years, increasing attention has been paid to the role of infectious agents in its pathogenesis. High-oncogenic viruses such as human papillomavirus (HPV), Epstein–Barr virus (EBV), and mouse mammary tumor virus (MMTV) are considered as possible factors involved in the development of the tumor process. Current studies confirm the ability of these viruses to disrupt cell cycle regulation, suppress antitumor mechanisms, and promote the malignant transformation of breast epithelial cells. However, the extent of their influence remains controversial and requires further multicenter investigations. The present article provides a review of recent literature devoted to the association of high-oncogenic viruses with breast cancer.

Keywords: breast cancer; high-oncogenic viruses; human papillomavirus; Epstein–Barr virus; MMTV; carcinogenesis

First page

634

Last page

641

For citation:Akhmatova G.R. - INFLUENCE OF HIGH-ONCOGENIC VIRUSES ON BREAST CANCER DEVELOPMENT//New Day in Medicine 10(84)2025 634-641 https://newdayworldmedicine.com/en/new_day_medicine/10-84-2025

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