93 -2 (40) 2022 — N.T.Yodgorova, F.Sh.Mamatmusaeva, — MICROBIOLOGICAL STATUS OF PATIENTS WITH COVID-19 WITH RESPIRATORY DISEASES

MICROBIOLOGICAL STATUS OF PATIENTS WITH COVID-19 WITH RESPIRATORY DISEASES

N.T.Yodgorova, Tashkent Medical Academy

F.Sh.Mamatmusaeva, Tashkent Medical Academy

S.T.Dzhumamurodov, Tashkent Medical Academy

Sh.B.Safarov Tashkent Medical Academy

Resume

Purpose of the study. To study The pathogens that cause purulent-inflammatory diseases of the upper respiratory tract in patients with COVID-19 are described. Materials and methods of research: In March-April 2021, swabs from the throat of 75 patients with COVID-19 infection, who were treated at the Republican Specialized Hospital 1 Zangiota, were examined at the Laboratory of SEA and Bacteriology of the Chilanzar district of Tashkent. Analysis and discussion of results.  34 women and 41 men. Of the 75 patients, 32 had mono-infections and 43 had poly-infections. Fungi (29%) and S. aureus (26%) made up the largest percentage. Of the conditionally pathogenic microorganisms Klebsiella pneumonia 13%, fungi 29%, Streptococcus spp. 10%, Pseudomonos aerogenosa 3%, St. epidermedis 12%. Conclusion. 77.1% of upper respiratory tract infections were detected between the ages of 31 and 80 years. According to the data obtained, the incidence of fungi (29%) was significantly higher due to the fact that patients used antibiotics more often and more randomly. In patients diagnosed with COVID-19, S.aureus was in the lead in 26%. According to the antibiotic efficacy of S. aureus, moxifloxin, cefazolin, cefoxitin, cefaperazones were twice as effective as ampecillin and benzylpecilin with a result of 83%

Key words: COVID-19, microorganisms, S. aureus, fungi, antibiotics.

First page

472

Last page

475

For citation: N.T.Yodgorova, F.Sh.Mamatmusaeva, S.T.Dzhumamurodov, Sh.B.Safarov MICROBIOLOGICAL STATUS OF PATIENTS WITH COVID-19 WITH RESPIRATORY DISEASES //New Day in Medicine 2(40)2022 472-475 https://clck.ru/eSRoq

LIST OF REFERENCES:

  1. Абдурахимов А., Эргашева З., Нугманов О., Усманов Х. COVID-19: патогенез и возможные решения проблемы (обзор литературы). // Rehealth journal. – 2020.-№ 2.2 (6).-С.171-173.
  2. Исмаилов Д.Д., Исаев Т.А., Шустов С.Б., Свёклина Т.С., Козлов В.А. Сравнительный анализ лабораторных данных пациентов, страдающих пневмонией, вызванной SARS-COV-2, и бактериальной пневмонией //Вестник Российской Военно-медицинской академии. – 2020.-№ 4(72).- С.53-59.
  3. Andrew Seaton R, Lesley Cooper. Antibiotic prescribing for respiratory tract infection in patients with suspected and proven COVID-19: results from an antibiotic point prevalence survey in Scottish hospitals JAC Antimicrob Resist doi:10.1093/jacamr/dlab078. 2021.-C.78-86.
  4. Coralina Garsiya -Vidal, Gemma Sanjun. Incidence of co-infections and superinfections in hospitalized patients with COVID-19: aretrospektive cohort study. Clinical Microbiology and Infection. 26.07.2020 page 85
  5. Chibabhai V., Duse A.G., Perovic O., Richards G.A. Collateral damage of the COVID-19 pandemic: Exacerbation of antimicrobial resistance and disruptions to antimicrobial stewardship programmes? //S Afr Med J. 2020 Jun 2; 110(7):572-573.
  6. Gerald J., Kost M.D. Geospatial Spread of Antimicrobial Resistance, Bacterial and Fungal Threats to Coronavirus Infectious Disease 2019 (COVID-19) Survival, and Point-of-Care Solutions Arch Pathol Lab Med. 2021;145:145–167; doi: 10.5858 arpa.2020-0284-RA
  7. Jie Li, Junwei Wang, Yi Yang. Etiology and antimicrobial resistance of secondary bacterial infections in patients hospitalized with COVID-19 in Wuhan, China: a retrospective analysis Li et al. Antimicrobial Resistance and Infection Control(2020) 9:153

file

download